Morbus Sjögren

nach Chisholm und Mason (J Clin Pathol 1968; 21: 656-660)

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Grading standard for labial salivary gland biopsy

GradeLymphocytes per 4 square mm of salivary tissue
0 Absent
1 Slight infiltrate
2 Moderate infiltrate or less than one focus
3 One focus
4 More than one focus

Focus = an aggregate of 50 or more lymphocytes and histiocytes